Not all polyetser resins are created equal, and neither are the methods used to build products from them.
You will get different blister results, or the potential for blisters, from the build method you choose, the same resin used in one way may result in no blisters, used in a different way and the potential for blisters may be higher.
But back to the resin end of it.
The standard low cost GP (general purpose) resin isn't designed for marine use, it's designed to be low in cost and provide adequate performance in a range of products, frequently low cost is the primary consideration. For a small skiff or a boat that doesn't sit in the water for long periods of time it can work well enough that you probably won't have any problems, on the hull of a boat that stays in the slip you might. This will frequently be a blended resin, ORTHO/DCPD.
A marine resin would typically be an ISO/DCPD blend, it will resist blistering a great deal better, and you typically won't have any issues. On larger boats that will live their entire life in the water you may want to upgrade from here though.
You can upgrade to using a VE skin resin in combination with either of the two prior resins and have very good results. Most of these skin resins are a VE/DCPD blend, but ther are straight VE's
VE barrier coats behind the gel coat can help eliminate blisters with any of the listed resin types, when used correctly the chances of having a hull blister would be very unlikely no matter how it was treated when these products are used.
Most marine grade gel coats will hold up just fine below the waterline.